LEWATIT® PH 1074 HEP
Lewatit® PH 1074 HEP is a macroporous, strongly basic (type I) anion exchange resin based on a crosslinked polyacrylate.
Lewatit® PH 1074 HEP is suitable for the decolorization of liquid sugar syrups and has been optimized for biopharmaceutical processing applications to reliably support the capture and purification of high molecular weight organic compounds deriving from sugar solutions or complex fermentation broth process solutions. In its chloride form Lewatit® PH 1074 HEP is suitable for applications such as:
- Decolorization of syrups from cane sugar production
- Capture and purification of antibiotics, e.g., vancomycin
- Heparin capture and purification, including heparin storage on resin
- Chondroitin sulfate capture and purification
- Nadroparin calcium capture and purification
- Dermatan sulfate capture and purification
- Decolorization of bioprocessing solutions, e.g., for peptides, antibiotics, small molecule API production
The macroporous structure and balanced resin matrix of Lewatit®
PH 1074 HEP facilitates the kinetics of adsorption and desorption, achieving highest adsorption capacities and ideal desorption properties. This is highly beneficial for recovery of high-molecular hydrophilic anionic organic substances, for example, from fermentation broths, such as required for heparin and other glycosaminoglycans. Elution is easily achieved by neutral or alkaline sodium chloride solution.
Information
Business Unit:
Liquid Purification Technologies
Product Group:
Ion Exchange Resin
Applications
- Extraction
- Food industry
- Pharmaceutical industry / Biotechnology
- Separation
